Genetic Hypertension: A direct link to salt
نویسندگان
چکیده
منابع مشابه
Genetic Hypertension: A direct link to salt
The basis of one type of inherited hypertension has been discovered-it is caused by mutations in the gene for the beta subunit of a renal sodium channel.
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The central roles of salt (NaCl) and the kidneys in the pathogenesis of most forms of hypertension are well established.1,2 The linkage between NaCl retention and blood pressure (BP) elevation is often referred to as “whole body autoregulation.”3,4 Surprisingly, however, the precise mechanisms that underlie this linkage (ie, the signaling pathway) have escaped elucidation. Here, we examined the...
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ژورنال
عنوان ژورنال: Current Biology
سال: 1995
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(95)00055-8